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Jason Winget

Contact Info

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Last updated on 2019-08-02.

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Jason Winget

Senior Scientist, Proteomics, LC-MS/MS, and Data Science

I am a PhD biochemist with 10 years of experience in proteomics, including quantitative shotgun and targeted approaches. I am a strong advocate for reproducible research and data integrity. My recent professional development has focused on best statistical practices for data analysis and interpretation, as well as clear and transparent communication of results.

I am particularly interested in opportunities with dynamic and energetic teams which leverage data science (statistical analysis and modeling) to provide deeper insights that address biological questions about mechanism of action and health.

Professional Experience

Senior Scientist

Procter & Gamble

Mason, OH, USA

Present - 2019

  • Technical lead for corporate proteomics program
  • Studied effects of cosmetics usage on epidermal health
  • Developed internal capability in Data-Independent Analysis (DIA)
  • Performed small organic chemical constitutent identification (CCID) to support current business needs
  • Leveraged proteogenomics to support naturals & botanicals program for Type I allergy program
  • Developed R Shiny applications and Rmarkdown templates to streamline repetitive data analysis tasks

Scientist

Procter & Gamble

Mason, OH, USA

2019 - 2016

  • Developed high throughput targeted proteomics assays to support clinical studies.
  • Spearheaded adoption of label-free proteomics approaches to refine safety assessments for Type-I allergy
  • Harmonized sample preparation, LC-MS/MS methods, and data analysis across studies
  • Taught “Introduction to R” courses

Research Scientist

Institute for Systems Biology

Seattle, WA, USA

2016 - 2014

  • Performed shotgun and targeted proteomic analysis of human epidermis
  • Developed software for label-free quantification

Postdoctoral Researcher

Institute for Systems Biology

Seattle, WA, USA

2014 - 2012

  • Method development for proteomic analysis of low protein yield clinical skin surface samples
  • Refined data processing parameters for samples containing highly homologous proteins

Postdoctoral Fellow

University of British Columbia

Vancouver, BC, Canada

2012 - 2009

  • Studied the ubiquitin & proteasome system
  • Mammalian cell culture
  • Immunofluorescence
  • Site-directed mutagenesis
  • Mentored several undergraduate researchers

Education

University of Delaware

Ph.D. in Biochemistry

Newark, DE, USA

2009 - 2002

Thesis advisor: Dr. Brian Bahnson. Research involved structural biology of G protein-coupled receptors and Phospholipase A2 membrane-associated enzymes. Awarded an NSF Integrative Graduate Research Traineeship (IGERT).

Florida State University

B.Sc. in Chemistry

Tallahassee, FL, USA

2002 - 1998

Selected Publications

Proteomic and bioinformatic analyses for the identification of proteins with low allergenic potential for hazard assessment

Toxicological Sciences 170 (1), 210-222

N/A

2019

Krutz NL, Winget JM, Ryan CA, Wimalasena R, Maurer-Stroh S, Dearman RJ, Kimber I, Gerberick GF

StPeter: Seamless label-free quantification with the trans-proteomic pipeline

Journal of proteome research 17 (3), 1314-1320

N/A

2018

Hoopmann MR, Winget JM, Mendoza L, Moritz RL

Quantitative proteomic analysis of stratum corneum dysfunction in adult chronic atopic dermatitis

The Journal of investigative dermatology 136 (8), 1732

N/A

2016

Winget JM, Finlay D, Mills KJ, Huggins T, Bascom C, Isfort RJ, Moritz RL

Quantitative proteogenomic profiling of epidermal barrier formation in vitro

Journal of dermatological science 78 (3), 173-180

N/A

2015

Winget JM, Watts JD, Hoopmann MR, DiColandrea T, Robinson MK, Huggins T, Bascom C, Isfort RJ, Moritz RL

The diversity of ubiquitin recognition: hot spots and varied specificity

Molecular cell 38 (5), 627-635

N/A

2010

Winget JM and Mayor T